The best museums in Amarillo in September 2025

These are the top 10 best museums in Amarillo, United States, ranked by their rating and popularity in 2025. Click a museum for more information about the museum, including visitor information, exhibitions and reviews.

For a complete overview of museums in Amarillo, their exhibitions and discount cards & passes, see our overview page with all museums in Amarillo.

Looking for the best museums in Amarillo? These are the best ones:

  1. Texas Air & Space Museum1

    Texas Air & Space Museum

     Amarillo, TX
    The Texas Air & Space Museum is an aviation museum situated near the Rick Husband Amarillo International Airport in Amarillo, Texas. This location makes it easily accessible for tourists, especially those who are flying into the city. The museum offers a unique opportunity to explore the history and development of aviation in the region.
  2. Don Harrington Discovery Center2

    Don Harrington Discovery Center

     Amarillo, TX
    The Don Harrington Discovery Center, located in Amarillo, Texas, is a nonprofit organization that serves as an interactive science center and planetarium. Named after philanthropist Don Harrington, the center is situated in the city's hospital district. It offers a variety of exhibits and programs that aim to educate and entertain visitors of all ages.
  3. American Quarter Horse Hall of Fame & Museum3

    American Quarter Horse Hall of Fame & Museum

     Amarillo, TX
    The American Quarter Horse Hall of Fame & Museum showcases a variety of exhibits. Visitors can view photographs of honorees and paintings of renowned American Quarter Horses, many of which were created by the western artist Orren Mixer. The museum also offers interactive exhibits about horse anatomy, horse riding, and the various disciplines of the American Quarter Horse.
  4. Harrington House4

    Harrington House

     Amarillo, TX
  5. Amarillo Zoo5

    Amarillo Zoo

     Amarillo, TX
    Enjoy a lovely family afternoon in the zoo admiring and learning about its lovely, fluffy, hairy, smelly and slimy inhabitants.
  6. Amarillo Museum of Art6

    Amarillo Museum of Art

     Amarillo, TX
    The Amarillo Museum of Art is situated at 2200 S. Van Buren Street, within the premises of Amarillo College in Amarillo city, Potter county, Texas. This location is easily accessible and provides a cultural hub within the city, making it a convenient and enriching stop for tourists.
  7. 7

    Amarillo Railroad Museum

     Amarillo, TX
  8. 8

    Kwahadi Museum of the American Indian

     Amarillo, TX
    This museum features lovely exhibits on Indian culture, like beadworks, paintings, bronzes, clothes and tools, all made by Thomas E. Mails.
  9. 9

    Texas Pharmacy Museum

     Amarillo, TX
    The largest museum in Texas focusing on the history of pharmacy, boasting a collection of more then 12,000 items over a century old.
  10. 10

    Jack Sisemore Traveland Rv Museum

     Amarillo, TX
    Are you a fan of RVs? Then this is your place. A free of charge museum with friendly staff with a passion for old recreational vehicles.

All museums in Amarillo