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The best museums in Spartanburg in September 2025

These are the top 5 best museums in Spartanburg, United States, ranked by their rating and popularity in 2025. Click a museum for more information about the museum, including visitor information, exhibitions and reviews.

For a complete overview of museums in Spartanburg, their exhibitions and discount cards & passes, see our overview page with all museums in Spartanburg.

Looking for the best museums in Spartanburg? These are the best ones:

  1. Seay House1

    Seay House

     Spartanburg, SC
    The Jammie Seay House, located in Spartanburg, South Carolina, is a historic home with a rich past. Constructed between 1770 and 1800, this one-story log house stands as a testament to the architectural style and craftsmanship of the period. Its historical significance is further underscored by its builder, Jammie Seay, a Revolutionary War soldier.
     4.1
    History & Anthropology History
  3. Chapman Cultural Center2

    Chapman Cultural Center

     Spartanburg, SC
     4.5
    History & Anthropology History
  4. 3

    Children's Museum of the Upstate - Spartanburg

     Spartanburg, SC
     4.5
    Specialized & Alternative Specialized
  5. 4

    Spartanburg Art Museum

     Spartanburg, SC
     4.5
    Art & Design Art
  6. 5

    Spartanburg Science Center

     Spartanburg, SC
     4.5
    Science & Technology Science

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