The best museums in Key West in September 2025

These are the top 20 best museums in Key West, United States, ranked by their rating and popularity in 2025. Click a museum for more information about the museum, including visitor information, exhibitions and reviews.

For a complete overview of museums in Key West, their exhibitions and discount cards & passes, see our overview page with all museums in Key West.

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Looking for the best museums in Key West? These are the best ones:

  1. The Ernest Hemmingway Home and Museum1

    The Ernest Hemmingway Home and Museum

     Key West, FL
    The Ernest Hemingway House, located in Key West, Florida, is a significant tourist attraction. This is the house where the renowned author Ernest Hemingway resided from 1931 to 1939. During his time here, he penned some of his most famous works, including 'The Snows of Kilimanjaro' and 'The Short Happy Life of Francis Macomber'.
  2. Truman Little White House2

    Truman Little White House

     Key West, FL
    The Harry S. Truman Little White House, located in Key West, Florida, served as the winter White House for President Harry S. Truman. The President spent a total of 175 days here during his 11 visits. This historical site offers a glimpse into the life and work of President Truman during his presidency.
  3. Key West Lighthouse & Keeper's Quarters Museum3

    Key West Lighthouse & Keeper's Quarters Museum

     Key West, FL
    The Key West Lighthouse, situated in Key West, Florida, boasts a rich history dating back to 1825. The original lighthouse was a 65-foot tower, a testament to the architectural prowess of the era.
  4. Fort East Martello Museum & Gardens4

    Fort East Martello Museum & Gardens

     Key West, FL
    The Martello Gallery-Key West Art and Historical Museum, also known as the East Martello Tower, is a historic site situated at 3501 South Roosevelt Boulevard in Key West, Florida. This location is steeped in history and offers a unique insight into the past of the region.
  5. Key West Butterfly & Nature Conservatory5

    Key West Butterfly & Nature Conservatory

     Key West, FL
    The Key West Butterfly and Nature Conservatory is a unique butterfly zoo situated on Duval Street in Key West, Florida. This location offers visitors the opportunity to experience a diverse range of butterfly species in a controlled environment.
  6. Key West Shipwreck Museum6

    Key West Shipwreck Museum

     Key West, FL
    The Key West Shipwreck Museum, previously known as the Shipwreck Historeum, is situated in the beautiful location of Key West, Florida. This museum offers a unique blend of actors, films, and real artifacts to narrate the 400-year-old story of shipwreck salvaging in the Florida Keys.
  7. Audubon House and Tropical Gardens7

    Audubon House and Tropical Gardens

     Key West, FL
    The Audubon House & Tropical Gardens is a historic site located at 205 Whitehead Street in Key West, Florida. This location is easily accessible and offers a unique experience for visitors interested in history, nature, and art.
  8. Key West Tropical Forest and Botanical Garden8

    Key West Tropical Forest and Botanical Garden

     Key West, FL
    The Key West Botanical Forest and Garden is a botanical garden and arboretum that spans 11 acres. It is located in Key West, Florida, in the United States. This lush, green space is a haven for nature lovers and those interested in botany. It offers a unique opportunity to explore a variety of plant species in a tropical setting.
  9. Fort Zachary Taylor Historic State Park9

    Fort Zachary Taylor Historic State Park

     Key West, FL
    Fort Zachary Taylor State Historic Park, colloquially known as Fort Taylor or Fort Zach, is a historic site and state park located near the city of Key West in Florida, United States. This former fort is a significant part of the region's history and offers visitors a glimpse into the past. It is a popular destination for those interested in history, nature, and outdoor activities.
  10. The Hemingway Home & Museum10

    The Hemingway Home & Museum

     Key West, FL
    The Ernest Hemingway Home & Museum is situated in Key West, Florida. This is the place where the renowned American writer Ernest Hemingway resided from 1927 to 1939. The house is a significant part of Hemingway's history and offers a glimpse into the life of the writer during his time in Florida.
  11. Mel Fisher Maritime Museum11

    Mel Fisher Maritime Museum

     Key West, FL
    The Mel Fisher Maritime Museum is situated at 200 Greene Street, Key West, Florida. This location is easily accessible and provides a convenient spot for tourists to explore the rich maritime history of the region.
  12. Key West Lighthouse12

    Key West Lighthouse

     Key West, FL
    The Key West Lighthouse, situated in Key West, Florida, boasts a rich history dating back to 1825. The original lighthouse was a 65-foot (20 m) tower, marking it as a significant historical landmark in the region.
  13. Old Post Office and Customshouse13

    Old Post Office and Customshouse

     Key West, FL
    The Custom House and Old Post Office is a historic site situated at 281 Front Street, Key West, Florida, United States. This location is easily accessible and offers a glimpse into the rich history of the area. It's a great place for tourists who are interested in history and architecture.
  14. Key West Museum of Art and History14

    Key West Museum of Art and History

     Key West, FL
    The Custom House and Old Post Office, located at 281 Front Street, Key West, Florida, is a historic site that holds significant importance. This location is not just a testament to the architectural prowess of the past, but also a symbol of the rich history of Key West.
  15. Key West Aquarium15

    Key West Aquarium

     Key West, FL
    The Key West Aquarium, located in Key West, Florida, is the only public aquarium in the area. This unique feature makes it a notable destination for tourists interested in marine life and aquatic exhibits.
  16. San Carlos Institute16

    San Carlos Institute

     Key West, FL
    The San Carlos Institute, also known as San Carlos, is a Cuban heritage center and museum situated at 516 Duval Street in Key West, Florida. This institute was established in 1871 by members of the Cuban exile community with the aim of preserving and promoting the language, cultural values, and patriotic ideals of the Cuban people. Today, it serves as a multi-purpose facility functioning as a museum, library, school, conference center, theater, and art gallery for the Key West community.
  17. 17

    Gallery On Greene

     Key West, FL
    An interesting collection of historical Key West art is to be seen here. Art connoisseurs should not miss out on it.
  18. Florida Keys Eco-Discovery Center18

    Florida Keys Eco-Discovery Center

     Key West, FL
    The Florida Keys Eco-Discovery Center, located in Key West, is a natural history museum. It provides an opportunity for visitors to explore and learn about the unique ecosystem of the region. The center is dedicated to educating the public about the importance of preserving the natural environment of the Florida Keys.
  19. Uscgc Ingham Maritime Museum19

    Uscgc Ingham Maritime Museum

     Key West, FL
    The USCGC Ingham (WPG/WAGC/WHEC-35) is a significant piece of maritime history, being one of only two preserved Treasury-class United States Coast Guard Cutters. This vessel stands as a testament to the rich history and heritage of the United States Coast Guard, offering visitors a unique opportunity to explore a piece of living history.
  20. 20

    Sails To Rails Museum at Flagler Station

     Key West, FL

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